Preclinical Form and Formulation for Drug Discovery (GRS)

The Preclinical Form and Formulation for Drug Discovery Gordon Research Seminar (GRS) serves as a distinctive platform fostering collaboration and dialogue among emerging researchers in the field of drug formulation. Designed specifically for young doctoral and post-doctoral researchers, this seminar allows attendees to present their work, engage in discussions about innovative methodologies, and share pre-published data.

The GRS is characterized by an interactive format, where experienced mentors and trainee moderators encourage active participation, ensuring that all attendees contribute to the scientific discourse rather than merely observing.

This year’s theme, Molecular Foundations and Emerging Strategies of Preclinical Formulation, spotlights the transition from fundamental molecular principles to practical formulation performance. The seminar will cover a wide array of topics, including synthetic molecules, biologics, and the use of mechanistic and computational tools to enhance our understanding of drug formulations.

Moreover, the GRS will explore advanced formulation strategies that extend beyond molecular considerations, showcasing novel excipients, enabling technologies, advanced processing methods, and AI-informed tools for next-generation delivery systems. The GRS will consist of multiple sessions, beginning with an introductory session followed by poster presentations and talks from selected registrants.

Session 1 will delve into the molecular foundations of drug formulation and delivery, emphasizing how molecular mechanisms influence formulation design and the development of innovative drug delivery strategies. Session 2 will highlight recent advancements in formulation development, including the implementation of digital tools and new therapeutic modalities, showcasing adaptations in formulation science amidst evolving challenges.

With approximately 10 talks and two dedicated poster sessions, all participants are expected to present their findings, either through oral presentations or poster displays, making the submission of an abstract a prerequisite for attendance. The seminar aims to facilitate networking and scientific growth, preparing participants for the adjacent Gordon Research Conference (GRC) themed Formulation at Interfaces of Discovery: AI-Native Design, Barrier Biology, and Emerging Modalities.

This GRS will take place at Bates College in Lewiston, United States, marking a significant opportunity for early-career researchers to engage deeply in scientific inquiry and collaboration within the drug discovery community.